| 2010 Softball All-Conference | ||
| Player of the Year: Megan Melbye | Kettle Moraine | Senior |
| 1st Team Pitcher | ||
| Amy Drewicz | Waukesha West | Junior |
| 2nd Team Pitcher | ||
| Lexi Economou | Arrowhead | Sophomore |
| 1st Tean Catcher | ||
| Sam Hastings | Waukesha West | Senior |
| 2nd Team Catcher | ||
| Whitney Williams | KIettle Moraine | Senior |
| Honorable Mention Catcher | ||
| Kristina Rodriguez | Catholic Memorial | Senior |
| Crystal Roe | Pius XI | Junior |
| Kelsie Knutson | Waukesha North | Sophomore |
| 1st Team 1st Base | ||
| Allyssa Hoppe | Pius XI | Junior |
| 2nd Team 1st Base | ||
| Sam Munich | Kettle Moraine | Senior |
| Honorable Mention 1st Base | ||
| Allie Gatchel | Arrowhead | Senior |
| Kristen Siekierski | Mukwonago | Sophomore |
| Kelsie Wendelberger | Waukesha North | Junior |
| Chandler Gloudeman | Waukesha West | Junior |
| 1st Team Infielder | ||
| Callyn Woldt | Arrowhead | Junior |
| Katie McCann | Kettle Moraine | Junior |
| Chelsea Gulbronson | Pius XI | Senior |
| 2nd Team Infielder | ||
| Lauren Krolikowski | Catholic Memorial | Sophomore |
| Brielle Bartes | Mukwonago | Senior |
| Kellee Laske | Pius XI | Senior |
| Heather Kascht | Waukesha West | Sophomore |
| Katie Landherr | Waukesha West | Junior |
| Honorable Mention Infielder | ||
| Jordy Brengosz | Arrowhead | Junior |
| Kara Olsen | Arrowhead | Freshman |
| Hannah Foltz | Kettle Moraine | Freshman |
| Sierra Flury | Mukwonago | Junior |
| Lacy Fons | Waukesha North | Freshman |
| Erika Johnson | Waukesha South | Senior |
| 1st Team Outfield | ||
| Shelby Hartig | Kettle Moraine | Senior |
| Rachel Larke | Waukesha South | Junior |
| Britanny Wright | Waukesha West | Junior |
| 2nd Team Outfield | ||
| Megan Culhane | Arrowhead | Senior |
| Carly Brengosz | Arrowhead | Freshman |
| Candace RupnickKettle Moraine | Junior | |
| Emily Sievert | Mukwonago | Senior |
| Amanda Braun | Pius XI | Senior |
| Honorable Mention Outfield | ||
| Tia Johnson | Catholic Memorial | Freshman |
| Kassi Carlsen | Waukesha South | Senior |
| 1st Team Utility | ||
| Kelly Sykes | Waukesha North | Sophomore |
| 2nd Team Utility | ||
| Danielle Williams | Mukwonago | Sophomore |
| Rebecca Holzbauer | Pius XI | Junior |
| Honorable Mention Utility | ||
| Maddie Goodwill | Arrowhead | Freshman |
| Kelly Venzke | Waukesha South | Sophomore |